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Microbiome analysis encompasses not only oral flora but also gut microbiota influences, as both interact through the oral-gut-brain axis to modulate neuropsychiatric disease pathogenesis (Hashimoto, 2023)

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Since the amount of the marker compounds that have been administered orally is known and the markers are not substantially metabolized during the study period, their urinary excretion is expressed as a percentage of the administered molecule ingested

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